HCSGD entry for FGF22

1. General information

Official gene symbolFGF22
Entrez ID27006
Gene full namefibroblast growth factor 22
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005104Fibroblast growth factor receptor bindingIEAmolecular_function
GO:0005576Extracellular regionIEA TAScellular_component
GO:0005615Extracellular spaceNAScellular_component
GO:0005730NucleolusIEAcellular_component
GO:0005794Golgi apparatusIEAcellular_component
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0008083Growth factor activityIEAmolecular_function
GO:0008286Insulin receptor signaling pathwayTASbiological_process
GO:0008543Fibroblast growth factor receptor signaling pathwayIEA TASbiological_process
GO:0009986Cell surfaceIEAcellular_component
GO:0030154Cell differentiationNASbiological_process
GO:0038095Fc-epsilon receptor signaling pathwayTASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0048015Phosphatidylinositol-mediated signalingTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.34841340370.92255498650.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0686547417
GSE13712_SHEARUp0.0504130890
GSE13712_STATICUp0.0367428968
GSE19018Up0.0213305019
GSE19899_A1Up0.0858994307
GSE19899_A2Up0.0296031315
PubMed_21979375_A1Up0.1610273258
PubMed_21979375_A2Down-0.1365250072
GSE35957Up0.0632207171
GSE36640Up0.1107796734
GSE54402Up0.0241792002
GSE9593Up0.1238037791
GSE43922Up0.1034924609
GSE24585Up0.2121793149
GSE37065Down-0.0772257727
GSE28863_A1Down-0.0727947853
GSE28863_A2Down-0.0699159294
GSE28863_A3Up0.6279447474
GSE28863_A4Up0.0844883054
GSE48662Up0.0492233664

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-132-3pMIMAT0000426MIRT021791MicroarrayFunctional MTI (Weak)17612493
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.