HCSGD entry for OPLAH
1. General information
| Official gene symbol | OPLAH |
|---|---|
| Entrez ID | 26873 |
| Gene full name | 5-oxoprolinase (ATP-hydrolysing) |
| Other gene symbols | 5-Opase OPLA OPLAHD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006750 | Glutathione biosynthetic process | TAS | biological_process |
| GO:0006805 | Xenobiotic metabolic process | TAS | biological_process |
| GO:0017168 | 5-oxoprolinase (ATP-hydrolyzing) activity | TAS | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:1901687 | Glutathione derivative biosynthetic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6460099920 | 0.3606217583 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2144566547 |
| GSE13712_SHEAR | Down | -0.0362587435 |
| GSE13712_STATIC | Down | -0.0540718458 |
| GSE19018 | Up | 0.2706974880 |
| GSE19899_A1 | Down | -0.1612448003 |
| GSE19899_A2 | Down | -0.3915259919 |
| PubMed_21979375_A1 | Up | 0.0845714322 |
| PubMed_21979375_A2 | Down | -0.3329898010 |
| GSE35957 | Down | -0.0622725520 |
| GSE36640 | Up | 0.0613701326 |
| GSE54402 | Up | 0.0837340013 |
| GSE9593 | Down | -0.2306947564 |
| GSE43922 | Up | 0.0028759801 |
| GSE24585 | Up | 0.1102314437 |
| GSE37065 | Down | -0.0312869074 |
| GSE28863_A1 | Up | 0.0432053330 |
| GSE28863_A2 | Down | -0.0538057913 |
| GSE28863_A3 | Up | 0.2838087313 |
| GSE28863_A4 | Up | 0.0258417500 |
| GSE48662 | Up | 0.2410061837 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Glutamic Acid | DB00142 | NUTR00027 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
