HCSGD entry for GDI1
1. General information
| Official gene symbol | GDI1 |
|---|---|
| Entrez ID | 2664 |
| Gene full name | GDP dissociation inhibitor 1 |
| Other gene symbols | 1A GDIL MRX41 MRX48 OPHN2 RABGD1A RABGDIA XAP-4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005092 | GDP-dissociation inhibitor activity | TAS | molecular_function |
| GO:0005093 | Rab GDP-dissociation inhibitor activity | IEA ISS | molecular_function |
| GO:0005096 | GTPase activator activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | TAS | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0017137 | Rab GTPase binding | IEA | molecular_function |
| GO:0030496 | Midbody | IDA | cellular_component |
| GO:0032482 | Rab protein signal transduction | ISS | biological_process |
| GO:0043005 | Neuron projection | IEA | cellular_component |
| GO:0043234 | Protein complex | IEA | cellular_component |
| GO:0050771 | Negative regulation of axonogenesis | ISS | biological_process |
| GO:0050790 | Regulation of catalytic activity | ISS TAS | biological_process |
| GO:0051056 | Regulation of small GTPase mediated signal transduction | TAS | biological_process |
| GO:0051592 | Response to calcium ion | IEA | biological_process |
| GO:0090315 | Negative regulation of protein targeting to membrane | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1384660309 | 0.5801264162 | 0.7488236972 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0314423790 |
| GSE13712_SHEAR | Up | 0.1080646778 |
| GSE13712_STATIC | Down | -0.0384038632 |
| GSE19018 | Up | 0.4738600575 |
| GSE19899_A1 | Up | 0.1471073456 |
| GSE19899_A2 | Up | 0.6662968605 |
| PubMed_21979375_A1 | Up | 0.0718480101 |
| PubMed_21979375_A2 | Up | 0.6565409350 |
| GSE35957 | Up | 0.0731456964 |
| GSE36640 | Up | 0.3321680894 |
| GSE54402 | Up | 0.3622420847 |
| GSE9593 | Up | 0.0202594180 |
| GSE43922 | Up | 0.0085018687 |
| GSE24585 | Up | 0.3949717583 |
| GSE37065 | Down | -0.0285336629 |
| GSE28863_A1 | Down | -0.3301053107 |
| GSE28863_A2 | Down | -0.4109239214 |
| GSE28863_A3 | Down | -0.4025064874 |
| GSE28863_A4 | Down | -0.1152205976 |
| GSE48662 | Down | -0.0305389767 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025345 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029357 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046698 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
