HCSGD entry for MSTN

1. General information

Official gene symbolMSTN
Entrez ID2660
Gene full namemyostatin
Other gene symbolsGDF8 MSLHP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005102Receptor bindingIPImolecular_function
GO:0005125Cytokine activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005615Extracellular spaceIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0007179Transforming growth factor beta receptor signaling pathwayIEAbiological_process
GO:0007517Muscle organ developmentTASbiological_process
GO:0008083Growth factor activityIEAmolecular_function
GO:0008201Heparin bindingIEAmolecular_function
GO:0009408Response to heatIEAbiological_process
GO:0009629Response to gravityIEAbiological_process
GO:0014732Skeletal muscle atrophyIEAbiological_process
GO:0014741Negative regulation of muscle hypertrophyIEAbiological_process
GO:0014850Response to muscle activityIEAbiological_process
GO:0022602Ovulation cycle processIEAbiological_process
GO:0033574Response to testosteroneIEAbiological_process
GO:0042802Identical protein bindingIPImolecular_function
GO:0043403Skeletal muscle tissue regenerationIEAbiological_process
GO:0043627Response to estrogenIEAbiological_process
GO:0045471Response to ethanolIEAbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0048632Negative regulation of skeletal muscle tissue growthIEAbiological_process
GO:0051384Response to glucocorticoidIEAbiological_process
GO:0051602Response to electrical stimulusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.32350272790.73634813650.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0719722153
GSE13712_SHEARDown-0.0057909154
GSE13712_STATICUp0.0305112956
GSE19018Up0.0951516371
GSE19899_A1Up0.1401576599
GSE19899_A2Up0.1453644709
PubMed_21979375_A1Down-0.2366696129
PubMed_21979375_A2Down-0.3039634141
GSE35957Down-0.0742009227
GSE36640Up0.0620841285
GSE54402Up0.0515240121
GSE9593Up0.1903632370
GSE43922Up0.0230953736
GSE24585Up0.0560815706
GSE37065Down-0.0174502043
GSE28863_A1Down-0.0333195406
GSE28863_A2Up1.1758100462
GSE28863_A3Down-0.4100827306
GSE28863_A4Up0.1050546347
GSE48662Down-0.0071219416

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

MYO-029DB05915 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.