HCSGD entry for INTS6
1. General information
| Official gene symbol | INTS6 |
|---|---|
| Entrez ID | 26512 |
| Gene full name | integrator complex subunit 6 |
| Other gene symbols | DBI-1 DDX26 DDX26A DICE1 HDB INT6 Notchl2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004888 | Transmembrane signaling receptor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0015629 | Actin cytoskeleton | IDA | cellular_component |
| GO:0016180 | SnRNA processing | IDA | biological_process |
| GO:0032039 | Integrator complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7160125527 | 0.3354950420 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1128927190 |
| GSE13712_SHEAR | Up | 0.3719574295 |
| GSE13712_STATIC | Up | 0.1079263306 |
| GSE19018 | Down | -0.2782351229 |
| GSE19899_A1 | Down | -0.1214669575 |
| GSE19899_A2 | Down | -0.2930753185 |
| PubMed_21979375_A1 | Up | 0.1182611517 |
| PubMed_21979375_A2 | Down | -0.2971456146 |
| GSE35957 | Down | -0.1290597313 |
| GSE36640 | Down | -0.2979399603 |
| GSE54402 | Up | 0.0209552101 |
| GSE9593 | Down | -0.0187730237 |
| GSE43922 | Up | 0.0356779517 |
| GSE24585 | Up | 0.5309878959 |
| GSE37065 | Up | 0.1064944855 |
| GSE28863_A1 | Up | 0.0605707998 |
| GSE28863_A2 | Down | -0.0448972505 |
| GSE28863_A3 | Down | -0.3015857037 |
| GSE28863_A4 | Up | 0.1627613773 |
| GSE48662 | Down | -0.1756859018 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020710 | Reporter assay;Other | Functional MTI | 20584899 |
| hsa-miR-1 | MIMAT0000416 | MIRT023673 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028529 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
