HCSGD entry for GCNT1
1. General information
| Official gene symbol | GCNT1 |
|---|---|
| Entrez ID | 2650 |
| Gene full name | glucosaminyl (N-acetyl) transferase 1, core 2 |
| Other gene symbols | C2GNT C2GNT-L C2GNT1 G6NT NACGT2 NAGCT2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | cellular_component |
| GO:0003829 | Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005802 | Trans-Golgi network | IDA | cellular_component |
| GO:0009101 | Glycoprotein biosynthetic process | IMP | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016266 | O-glycan processing | TAS | biological_process |
| GO:0031985 | Golgi cisterna | IDA | cellular_component |
| GO:0032868 | Response to insulin | IEA | biological_process |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0048729 | Tissue morphogenesis | IEA | biological_process |
| GO:0050901 | Leukocyte tethering or rolling | IMP | biological_process |
| GO:0060352 | Cell adhesion molecule production | IMP | biological_process |
| GO:0060993 | Kidney morphogenesis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9848163558 | 0.0001551195 | 0.9999902473 | 0.0223109290 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3517018164 |
| GSE13712_SHEAR | Down | -1.6549189608 |
| GSE13712_STATIC | Down | -1.3578116478 |
| GSE19018 | Down | -0.0187040160 |
| GSE19899_A1 | Down | -0.2983496594 |
| GSE19899_A2 | Down | -2.5695912717 |
| PubMed_21979375_A1 | Down | -2.0377604596 |
| PubMed_21979375_A2 | Down | -1.5806628196 |
| GSE35957 | Down | -0.6184705410 |
| GSE36640 | Down | -3.2464818829 |
| GSE54402 | Down | -2.7270526950 |
| GSE9593 | Down | -0.4691719974 |
| GSE43922 | Down | -0.7890094576 |
| GSE24585 | Down | -0.6940390344 |
| GSE37065 | Down | -0.1813148791 |
| GSE28863_A1 | Up | 0.5758647336 |
| GSE28863_A2 | Down | -0.0518938398 |
| GSE28863_A3 | Down | -0.3430710256 |
| GSE28863_A4 | Up | 0.3289807966 |
| GSE48662 | Down | -0.2577344728 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-132-3p | MIMAT0000426 | MIRT021750 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-181a-5p | MIMAT0000256 | MIRT025075 | Microarray | Functional MTI (Weak) | 17612493 |
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