HCSGD entry for NUPR1
1. General information
| Official gene symbol | NUPR1 |
|---|---|
| Entrez ID | 26471 |
| Gene full name | nuclear protein, transcriptional regulator, 1 |
| Other gene symbols | COM1 P8 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002526 | Acute inflammatory response | IEA | biological_process |
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006461 | Protein complex assembly | IEA | biological_process |
| GO:0006473 | Protein acetylation | IEA | biological_process |
| GO:0008584 | Male gonad development | IEA | biological_process |
| GO:0009636 | Response to toxic substance | IEA | biological_process |
| GO:0016049 | Cell growth | IDA | biological_process |
| GO:0031401 | Positive regulation of protein modification process | IEA | biological_process |
| GO:0035914 | Skeletal muscle cell differentiation | IEA | biological_process |
| GO:0042771 | Intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | IEA | biological_process |
| GO:0043065 | Positive regulation of apoptotic process | IEA | biological_process |
| GO:0045786 | Negative regulation of cell cycle | IEA | biological_process |
| GO:0048147 | Negative regulation of fibroblast proliferation | IEA | biological_process |
| GO:2000194 | Regulation of female gonad development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3697065993 | 0.0005127541 | 0.9999902473 | 0.0417003086 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2760367212 |
| GSE13712_SHEAR | Down | -0.6102503086 |
| GSE13712_STATIC | Down | -0.5681334064 |
| GSE19018 | Up | 0.0074269003 |
| GSE19899_A1 | Down | -1.6067689527 |
| GSE19899_A2 | Down | -4.2004193874 |
| PubMed_21979375_A1 | Down | -3.9356647526 |
| PubMed_21979375_A2 | Down | -5.6722389598 |
| GSE35957 | Up | 0.1732112285 |
| GSE36640 | Up | 0.2732571963 |
| GSE54402 | Down | -3.1656140053 |
| GSE9593 | Up | 1.0921060386 |
| GSE43922 | Down | -1.4478540800 |
| GSE24585 | Up | 0.0085520434 |
| GSE37065 | Down | -0.0674445309 |
| GSE28863_A1 | Up | 0.0346022733 |
| GSE28863_A2 | Down | -0.2866648362 |
| GSE28863_A3 | Up | 0.6838859151 |
| GSE28863_A4 | Up | 0.2032904522 |
| GSE48662 | Up | 0.5187180557 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018204 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022819 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040412 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
