HCSGD entry for PTPN18
1. General information
| Official gene symbol | PTPN18 |
|---|---|
| Entrez ID | 26469 |
| Gene full name | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
| Other gene symbols | BDP1 PTP-HSCF |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004725 | Protein tyrosine phosphatase activity | IEA | molecular_function |
| GO:0004726 | Non-membrane spanning protein tyrosine phosphatase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006470 | Protein dephosphorylation | TAS | biological_process |
| GO:0035335 | Peptidyl-tyrosine dephosphorylation | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9279632233 | 0.2785960108 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0137772818 |
| GSE13712_SHEAR | Down | -0.0460771649 |
| GSE13712_STATIC | Down | -0.1319122441 |
| GSE19018 | Up | 0.2470907057 |
| GSE19899_A1 | Down | -0.0720052165 |
| GSE19899_A2 | Down | -0.0207696795 |
| PubMed_21979375_A1 | Down | -0.2144846107 |
| PubMed_21979375_A2 | Down | -0.1505877467 |
| GSE35957 | Down | -0.3282000759 |
| GSE36640 | Down | -0.5271444909 |
| GSE54402 | Down | -0.0972011404 |
| GSE9593 | Down | -0.1952835086 |
| GSE43922 | Up | 0.0525238845 |
| GSE24585 | Up | 0.1955367178 |
| GSE37065 | Down | -0.2517130544 |
| GSE28863_A1 | Down | -0.0731743089 |
| GSE28863_A2 | Up | 0.1921090731 |
| GSE28863_A3 | Up | 0.0279135320 |
| GSE28863_A4 | Down | -0.0874143857 |
| GSE48662 | Down | -0.1764772688 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT051290 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
