HCSGD entry for GCGR

1. General information

Official gene symbolGCGR
Entrez ID2642
Gene full nameglucagon receptor
Other gene symbolsGGR
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004967Glucagon receptor activityIDA IEAmolecular_function
GO:0005085Guanyl-nucleotide exchange factor activityTASmolecular_function
GO:0005768EndosomeIEAcellular_component
GO:0005886Plasma membraneIEA TAScellular_component
GO:0005887Integral component of plasma membraneIDAcellular_component
GO:0006091Generation of precursor metabolites and energyTASbiological_process
GO:0006112Energy reserve metabolic processTASbiological_process
GO:0006887ExocytosisIEAbiological_process
GO:0007188Adenylate cyclase-modulating G-protein coupled receptor signaling pathwayIMPbiological_process
GO:0007189Adenylate cyclase-activating G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0007584Response to nutrientTASbiological_process
GO:0008217Regulation of blood pressureTASbiological_process
GO:0009755Hormone-mediated signaling pathwayIEAbiological_process
GO:0016021Integral component of membraneIEA TAScellular_component
GO:0017046Peptide hormone bindingIEAmolecular_function
GO:0042593Glucose homeostasisIEA ISSbiological_process
GO:0042594Response to starvationIEA ISSbiological_process
GO:0043087Regulation of GTPase activityTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0070873Regulation of glycogen metabolic processIEA ISSbiological_process
GO:0071377Cellular response to glucagon stimulusIDA TASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.39572990010.91089231410.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0098204484
GSE13712_SHEARUp0.0215663275
GSE13712_STATICUp0.0362289906
GSE19018Up0.1277407294
GSE19899_A1Down-0.0177128242
GSE19899_A2Down-0.0472174765
PubMed_21979375_A1Down-0.3014438430
PubMed_21979375_A2Down-0.1348762713
GSE35957Up0.3625269985
GSE36640Down-0.0954352044
GSE54402Down-0.0007726945
GSE9593Up0.0949329446
GSE43922Up0.0580540000
GSE24585Up0.0871545154
GSE37065Down-0.0661453375
GSE28863_A1Up0.0569000320
GSE28863_A2Up0.1425105076
GSE28863_A3Up0.4081840311
GSE28863_A4Up0.1755275015
GSE48662Up0.1170087937

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Glucagon recombinantDB00040 BTD00057 | BIOD00057

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.