HCSGD entry for GCDH

1. General information

Official gene symbolGCDH
Entrez ID2639
Gene full nameglutaryl-CoA dehydrogenase
Other gene symbolsACAD5 GCD
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000062Fatty-acyl-CoA bindingIEAmolecular_function
GO:0003995Acyl-CoA dehydrogenase activityIEAmolecular_function
GO:0004361Glutaryl-CoA dehydrogenase activityEXPmolecular_function
GO:0005739MitochondrionTAScellular_component
GO:0005743Mitochondrial inner membraneIEAcellular_component
GO:0005759Mitochondrial matrixTAScellular_component
GO:0006554Lysine catabolic processTASbiological_process
GO:0006568Tryptophan metabolic processIEAbiological_process
GO:0016627Oxidoreductase activity, acting on the CH-CH group of donorsIEAmolecular_function
GO:0019395Fatty acid oxidationIEAbiological_process
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046949Fatty-acyl-CoA biosynthetic processIEAbiological_process
GO:0050660Flavin adenine dinucleotide bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.99389901600.02220039510.99999024730.2864271659

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0240643236
GSE13712_SHEARDown-0.2172636281
GSE13712_STATICDown-0.6554893521
GSE19018Down-0.1515748982
GSE19899_A1Down-0.5650229951
GSE19899_A2Down-0.4709948159
PubMed_21979375_A1Down-0.2572772913
PubMed_21979375_A2Down-0.6533089724
GSE35957Down-0.3635357637
GSE36640Down-0.3010370082
GSE54402Down-0.1546638233
GSE9593Down-0.8755495265
GSE43922Down-0.1456891484
GSE24585Up0.0906064127
GSE37065Down-0.1999314681
GSE28863_A1Down-0.0276854237
GSE28863_A2Down-0.1907971777
GSE28863_A3Down-0.0694033826
GSE28863_A4Up0.0750719850
GSE48662Up0.0386427330

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

S-4-Nitrobutyryl-CoaDB03245 EXPT02298

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.