HCSGD entry for GC
1. General information
| Official gene symbol | GC |
|---|---|
| Entrez ID | 2638 |
| Gene full name | group-specific component (vitamin D binding protein) |
| Other gene symbols | DBP DBP/GC GRD3 VDBG VDBP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IPI | molecular_function |
| GO:0005499 | Vitamin D binding | IEA TAS | molecular_function |
| GO:0005576 | Extracellular region | NAS TAS | cellular_component |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0008202 | Steroid metabolic process | TAS | biological_process |
| GO:0042359 | Vitamin D metabolic process | IEA TAS | biological_process |
| GO:0043202 | Lysosomal lumen | TAS | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0051180 | Vitamin transport | TAS | biological_process |
| GO:0051183 | Vitamin transporter activity | IEA | molecular_function |
| GO:1902118 | Calcidiol binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5966897496 | 0.8071149690 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0529846508 |
| GSE13712_SHEAR | Down | -0.0049628707 |
| GSE13712_STATIC | Up | 0.0172801720 |
| GSE19018 | Down | -0.2796345852 |
| GSE19899_A1 | Up | 0.2361143642 |
| GSE19899_A2 | Up | 0.2336599436 |
| PubMed_21979375_A1 | Up | 0.0099522112 |
| PubMed_21979375_A2 | Down | -0.1462952037 |
| GSE35957 | Up | 0.0497309588 |
| GSE36640 | Up | 0.1072317074 |
| GSE54402 | Up | 0.0098718992 |
| GSE9593 | Up | 0.1788490752 |
| GSE43922 | Up | 0.0194052339 |
| GSE24585 | Down | -0.0086139527 |
| GSE37065 | Up | 0.0632397025 |
| GSE28863_A1 | Up | 0.0210244869 |
| GSE28863_A2 | Up | 0.0647230787 |
| GSE28863_A3 | Up | 0.0237020445 |
| GSE28863_A4 | Up | 0.0215237603 |
| GSE48662 | Down | -0.0154894293 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016788 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
