HCSGD entry for GBX2

1. General information

Official gene symbolGBX2
Entrez ID2637
Gene full namegastrulation brain homeobox 2
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001569Patterning of blood vesselsIEAbiological_process
GO:0001755Neural crest cell migrationIEAbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007399Nervous system developmentTASbiological_process
GO:0007411Axon guidanceIEAbiological_process
GO:0021549Cerebellum developmentIEAbiological_process
GO:0021555Midbrain-hindbrain boundary morphogenesisIEAbiological_process
GO:0021568Rhombomere 2 developmentIEAbiological_process
GO:0021794Thalamus developmentIEAbiological_process
GO:0021884Forebrain neuron developmentIEAbiological_process
GO:0021930Cerebellar granule cell precursor proliferationIEAbiological_process
GO:0042472Inner ear morphogenesisIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0048483Autonomic nervous system developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.23204886590.77824753620.91569971531.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1361054239
GSE13712_SHEARDown-0.3512999238
GSE13712_STATICDown-0.2887510978
GSE19018Up0.2777575959
GSE19899_A1Up0.1594857020
GSE19899_A2Up0.1549965395
PubMed_21979375_A1Down-0.3746465452
PubMed_21979375_A2Down-0.0696694263
GSE35957Down-0.0290503269
GSE36640Up0.8205292820
GSE54402Down-0.1535403306
GSE9593Up0.1014472843
GSE43922Up0.1742746800
GSE24585Up0.3049312403
GSE37065Down-0.0555039759
GSE28863_A1Down-0.3800508438
GSE28863_A2Up0.2151557522
GSE28863_A3Up0.2964729036
GSE28863_A4Up0.1743027284
GSE48662Up0.0429199628

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017008MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.