HCSGD entry for GATM
1. General information
| Official gene symbol | GATM |
|---|---|
| Entrez ID | 2628 |
| Gene full name | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| Other gene symbols | AGAT AT |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IEA | cellular_component |
| GO:0005758 | Mitochondrial intermembrane space | IDA TAS | cellular_component |
| GO:0006600 | Creatine metabolic process | TAS | biological_process |
| GO:0006601 | Creatine biosynthetic process | IDA IEA | biological_process |
| GO:0006979 | Response to oxidative stress | IEA | biological_process |
| GO:0007584 | Response to nutrient | IEA | biological_process |
| GO:0009790 | Embryo development | IEA | biological_process |
| GO:0015067 | Amidinotransferase activity | IEA | molecular_function |
| GO:0015068 | Glycine amidinotransferase activity | IDA TAS | molecular_function |
| GO:0016813 | Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines | IEA | molecular_function |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0042246 | Tissue regeneration | IEA | biological_process |
| GO:0043434 | Response to peptide hormone | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046689 | Response to mercury ion | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9204186885 | 0.4515721363 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0025533115 |
| GSE13712_SHEAR | Down | -0.0386753512 |
| GSE13712_STATIC | Up | 0.0355156156 |
| GSE19018 | Up | 0.0073375329 |
| GSE19899_A1 | Up | 0.0657048236 |
| GSE19899_A2 | Up | 0.0318530764 |
| PubMed_21979375_A1 | Up | 0.1069251236 |
| PubMed_21979375_A2 | Down | -0.0037985712 |
| GSE35957 | Down | -0.0127281334 |
| GSE36640 | Up | 0.0493839585 |
| GSE54402 | Up | 0.0315081138 |
| GSE9593 | Up | 0.0015841972 |
| GSE43922 | Up | 0.0126719180 |
| GSE24585 | Down | -0.2585924535 |
| GSE37065 | Up | 0.0673850384 |
| GSE28863_A1 | Down | -0.3923469706 |
| GSE28863_A2 | Down | -0.3617721552 |
| GSE28863_A3 | Up | 0.2396734987 |
| GSE28863_A4 | Up | 0.0343214846 |
| GSE48662 | Down | -0.1147132079 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Ornithine | DB00129 | NUTR00043 |
| Glycine | DB00145 | NUTR00028 |
| Delta-Amino Valeric Acid | DB02068 | EXPT01116 |
| Gamma(Amino)-Butyric Acid | DB02530 | EXPT00402 |
| Norvaline | DB04185 | EXPT02397 |
| Alpha-Aminobutyric Acid | DB04454 | EXPT00390 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT021061 | Reporter assay;Other | Functional MTI | 20584899 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT021061 | Reporter assay;Other | Functional MTI | 18668040 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024805 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026928 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
