HCSGD entry for PLA2G2D
1. General information
| Official gene symbol | PLA2G2D |
|---|---|
| Entrez ID | 26279 |
| Gene full name | phospholipase A2, group IID |
| Other gene symbols | PLA2IID SPLASH sPLA2-IID sPLA2S |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004623 | Phospholipase A2 activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006654 | Phosphatidic acid biosynthetic process | TAS | biological_process |
| GO:0006954 | Inflammatory response | TAS | biological_process |
| GO:0016042 | Lipid catabolic process | IEA | biological_process |
| GO:0036148 | Phosphatidylglycerol acyl-chain remodeling | TAS | biological_process |
| GO:0036149 | Phosphatidylinositol acyl-chain remodeling | TAS | biological_process |
| GO:0036150 | Phosphatidylserine acyl-chain remodeling | TAS | biological_process |
| GO:0036151 | Phosphatidylcholine acyl-chain remodeling | TAS | biological_process |
| GO:0036152 | Phosphatidylethanolamine acyl-chain remodeling | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046474 | Glycerophospholipid biosynthetic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6567891607 | 0.5733655484 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0851977257 |
| GSE13712_SHEAR | Down | -0.0277057601 |
| GSE13712_STATIC | Down | -0.1092587115 |
| GSE19018 | Down | -0.0185157308 |
| GSE19899_A1 | Up | 0.0402576373 |
| GSE19899_A2 | Down | -0.0089390284 |
| PubMed_21979375_A1 | Up | 0.1675649557 |
| PubMed_21979375_A2 | Down | -0.0577471398 |
| GSE35957 | Up | 0.0955542786 |
| GSE36640 | Down | -0.1098307504 |
| GSE54402 | Down | -0.0509333279 |
| GSE9593 | Down | -0.0180795652 |
| GSE43922 | Up | 0.2333707432 |
| GSE24585 | Up | 0.1024353563 |
| GSE37065 | Down | -0.0909942420 |
| GSE28863_A1 | Down | -0.3152887922 |
| GSE28863_A2 | Down | -0.1230454570 |
| GSE28863_A3 | Up | 0.1858022581 |
| GSE28863_A4 | Up | 0.3218939044 |
| GSE48662 | Down | -0.0103216563 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Stearic acid | DB03193 | EXPT02965 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-15a-5p | MIMAT0000068 | MIRT051311 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
