HCSGD entry for FBXO8
1. General information
| Official gene symbol | FBXO8 |
|---|---|
| Entrez ID | 26269 |
| Gene full name | F-box protein 8 |
| Other gene symbols | FBS FBX8 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000151 | Ubiquitin ligase complex | IEA NAS | cellular_component |
| GO:0005086 | ARF guanyl-nucleotide exchange factor activity | IBA IEA | molecular_function |
| GO:0005634 | Nucleus | IBA | cellular_component |
| GO:0005802 | Trans-Golgi network | IBA | cellular_component |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | IEA NAS | biological_process |
| GO:0016192 | Vesicle-mediated transport | IBA | biological_process |
| GO:0030036 | Actin cytoskeleton organization | IBA | biological_process |
| GO:0030054 | Cell junction | IBA | cellular_component |
| GO:0032012 | Regulation of ARF protein signal transduction | IEA | biological_process |
| GO:0043087 | Regulation of GTPase activity | IBA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7365226435 | 0.0330495308 | 0.9999902473 | 0.3434687722 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0315256604 |
| GSE13712_SHEAR | Down | -0.1164181880 |
| GSE13712_STATIC | Down | -0.0153226590 |
| GSE19018 | Up | 0.8126609304 |
| GSE19899_A1 | Down | -0.4083229609 |
| GSE19899_A2 | Down | -0.8260611879 |
| PubMed_21979375_A1 | Down | -0.3018252808 |
| PubMed_21979375_A2 | Down | -0.7695714893 |
| GSE35957 | Down | -0.0056279392 |
| GSE36640 | Up | 0.0480044942 |
| GSE54402 | Down | -0.2468033748 |
| GSE9593 | Up | 0.1489929920 |
| GSE43922 | Down | -0.2551284438 |
| GSE24585 | Up | 0.4295297890 |
| GSE37065 | Up | 0.1085259243 |
| GSE28863_A1 | Down | -0.1063374034 |
| GSE28863_A2 | Down | -0.0977308841 |
| GSE28863_A3 | Down | -0.7618740286 |
| GSE28863_A4 | Down | -0.3117383945 |
| GSE48662 | Down | -0.3098444093 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019812 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031200 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
