HCSGD entry for FBXW8


1. General information

Official gene symbolFBXW8
Entrez ID26259
Gene full nameF-box and WD repeat domain containing 8
Other gene symbolsFBW6 FBW8 FBX29 FBXO29 FBXW6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005794Golgi apparatusIDAcellular_component
GO:0007030Golgi organizationIGI ISSbiological_process
GO:0019005SCF ubiquitin ligase complexIEAcellular_component
GO:0031467Cul7-RING ubiquitin ligase complexIDAcellular_component
GO:0048471Perinuclear region of cytoplasmIDAcellular_component
GO:0050775Positive regulation of dendrite morphogenesisIDA ISSbiological_process
GO:0060712Spongiotrophoblast layer developmentIEAbiological_process
GO:0060716Labyrinthine layer blood vessel developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.98876883100.01222762050.99999024730.2181987797

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1285961943
GSE13712_SHEARUp0.0311319055
GSE13712_STATICDown-0.2350140959
GSE19018Down-0.2610251266
GSE19899_A1Down-0.3276604082
GSE19899_A2Down-0.9512894029
PubMed_21979375_A1Down-1.3572395709
PubMed_21979375_A2Down-1.4094422510
GSE35957Down-0.1287572983
GSE36640Down-0.0087697607
GSE54402Down-0.3818581735
GSE9593Down-0.1979435177
GSE43922Down-0.6028903211
GSE24585Up0.2206372144
GSE37065Down-0.2323916832
GSE28863_A1Up0.0925186118
GSE28863_A2Down-0.0855359741
GSE28863_A3Down-0.3932521925
GSE28863_A4Down-0.1619574213
GSE48662Down-0.0457103181

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.