HCSGD entry for FBXO2

1. General information

Official gene symbolFBXO2
Entrez ID26232
Gene full nameF-box protein 2
Other gene symbolsFBG1 FBX2 Fbs1 NFB42 OCP1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001540Beta-amyloid bindingIEAmolecular_function
GO:0001948Glycoprotein bindingIEAmolecular_function
GO:0004842Ubiquitin-protein ligase activityTASmolecular_function
GO:0005783Endoplasmic reticulumIEAcellular_component
GO:0005829CytosolISScellular_component
GO:0006464Cellular protein modification processTASbiological_process
GO:0006508ProteolysisTASbiological_process
GO:0006516Glycoprotein catabolic processISSbiological_process
GO:0008285Negative regulation of cell proliferationIEAbiological_process
GO:0016567Protein ubiquitinationISSbiological_process
GO:0019005SCF ubiquitin ligase complexISScellular_component
GO:0030246Carbohydrate bindingIEAmolecular_function
GO:0030433ER-associated ubiquitin-dependent protein catabolic processIEAbiological_process
GO:0031090Organelle membraneIEAcellular_component
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic processISSbiological_process
GO:0031396Regulation of protein ubiquitinationIEAbiological_process
GO:0043197Dendritic spineIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.07021833520.97565397970.56610456361.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0645169636
GSE13712_SHEARDown-0.3078883723
GSE13712_STATICDown-0.0386842035
GSE19018Up0.2406074971
GSE19899_A1Up0.0566953617
GSE19899_A2Up0.0143956415
PubMed_21979375_A1Up0.6310633956
PubMed_21979375_A2Up0.1120241455
GSE35957Up0.1838708223
GSE36640Up0.8610279694
GSE54402Up0.0777582258
GSE9593Up0.1757215295
GSE43922Up0.1146782696
GSE24585Up0.2844284447
GSE37065Up0.1125514463
GSE28863_A1Down-0.1308569983
GSE28863_A2Up0.0621606247
GSE28863_A3Up0.3406064202
GSE28863_A4Up0.1577929278
GSE48662Up0.4852978241

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.