HCSGD entry for FBXL3
1. General information
| Official gene symbol | FBXL3 |
|---|---|
| Entrez ID | 26224 |
| Gene full name | F-box and leucine-rich repeat protein 3 |
| Other gene symbols | FBL3 FBL3A FBXL3A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000151 | Ubiquitin ligase complex | NAS | cellular_component |
| GO:0004842 | Ubiquitin-protein ligase activity | IDA NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | ISS | cellular_component |
| GO:0005829 | Cytosol | ISS | cellular_component |
| GO:0016567 | Protein ubiquitination | ISS NAS | biological_process |
| GO:0019005 | SCF ubiquitin ligase complex | IDA | cellular_component |
| GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | IDA | biological_process |
| GO:0042752 | Regulation of circadian rhythm | IMP | biological_process |
| GO:0043153 | Entrainment of circadian clock by photoperiod | ISS | biological_process |
| GO:0048511 | Rhythmic process | IEA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8956363360 | 0.1060848980 | 0.9999902473 | 0.6235033936 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1560661024 |
| GSE13712_SHEAR | Up | 0.3331495842 |
| GSE13712_STATIC | Down | -0.0064824245 |
| GSE19018 | Up | 0.1865861811 |
| GSE19899_A1 | Down | -0.1204838115 |
| GSE19899_A2 | Down | -0.3483444699 |
| PubMed_21979375_A1 | Up | 0.1732608379 |
| PubMed_21979375_A2 | Down | -0.3133468384 |
| GSE35957 | Up | 0.0238640809 |
| GSE36640 | Down | -0.1397437884 |
| GSE54402 | Down | -0.0953950404 |
| GSE9593 | Up | 0.1665569634 |
| GSE43922 | Down | -0.2350949887 |
| GSE24585 | Up | 0.4106266136 |
| GSE37065 | Up | 0.0034773659 |
| GSE28863_A1 | Down | -0.0984785232 |
| GSE28863_A2 | Down | -0.1651254212 |
| GSE28863_A3 | Down | -0.5771875849 |
| GSE28863_A4 | Up | 0.0105706440 |
| GSE48662 | Down | -0.7495998095 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-340-5p | MIMAT0004692 | MIRT019641 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT021110 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028091 | Sequencing | Functional MTI (Weak) | 20371350 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
