HCSGD entry for FBXW2
1. General information
| Official gene symbol | FBXW2 |
|---|---|
| Entrez ID | 26190 |
| Gene full name | F-box and WD repeat domain containing 2 |
| Other gene symbols | FBW2 Fwd2 Md6 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006464 | Cellular protein modification process | TAS | biological_process |
| GO:0006508 | Proteolysis | TAS | biological_process |
| GO:0016567 | Protein ubiquitination | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5504003267 | 0.6953727024 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1353037949 |
| GSE13712_SHEAR | Up | 0.2824604730 |
| GSE13712_STATIC | Up | 0.1000038043 |
| GSE19018 | Down | -0.1183802988 |
| GSE19899_A1 | Up | 0.0565556578 |
| GSE19899_A2 | Down | -0.0623318662 |
| PubMed_21979375_A1 | Down | -0.2502713852 |
| PubMed_21979375_A2 | Up | 0.1094652611 |
| GSE35957 | Up | 0.3512444698 |
| GSE36640 | Up | 0.1808841249 |
| GSE54402 | Down | -0.1241920982 |
| GSE9593 | Up | 0.1669942045 |
| GSE43922 | Up | 0.0353174888 |
| GSE24585 | Up | 0.1022835372 |
| GSE37065 | Down | -0.2256790688 |
| GSE28863_A1 | Up | 0.2667863175 |
| GSE28863_A2 | Up | 0.1857003453 |
| GSE28863_A3 | Down | -0.5375088254 |
| GSE28863_A4 | Up | 0.1251186677 |
| GSE48662 | Down | -0.0973640768 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024395 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026356 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-484 | MIMAT0002174 | MIRT041688 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT044308 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046735 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052115 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052421 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
