HCSGD entry for SERBP1
1. General information
| Official gene symbol | SERBP1 |
|---|---|
| Entrez ID | 26135 |
| Gene full name | SERPINE1 mRNA binding protein 1 |
| Other gene symbols | CHD3IP HABP4L PAI-RBP1 PAIRBP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003730 | MRNA 3'-UTR binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0042981 | Regulation of apoptotic process | IEA | biological_process |
| GO:0043488 | Regulation of mRNA stability | NAS | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8810031458 | 0.0847737472 | 0.9999902473 | 0.5529906258 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2042923979 |
| GSE13712_SHEAR | Down | -0.2011306952 |
| GSE13712_STATIC | Down | -0.0870946439 |
| GSE19018 | Down | -0.4240614342 |
| GSE19899_A1 | Up | 0.0121414274 |
| GSE19899_A2 | Down | -0.1025957124 |
| PubMed_21979375_A1 | Down | -0.1559954714 |
| PubMed_21979375_A2 | Up | 0.0738394978 |
| GSE35957 | Down | -0.1036428890 |
| GSE36640 | Down | -0.5322675959 |
| GSE54402 | Up | 0.0450194471 |
| GSE9593 | Down | -0.2943695060 |
| GSE43922 | Up | 0.0514291323 |
| GSE24585 | Down | -0.5021609775 |
| GSE37065 | Down | -0.2446522218 |
| GSE28863_A1 | Down | -0.0879472340 |
| GSE28863_A2 | Up | 0.3360649319 |
| GSE28863_A3 | Up | 0.2262074015 |
| GSE28863_A4 | Up | 0.1931259328 |
| GSE48662 | Down | -0.3899019481 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26a-5p | MIMAT0000082 | MIRT002315 | Immunoprecipitaion//Luciferase reporter assay//Western blot | Functional MTI | 17637574 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT025598 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT025598 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031433 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-93-3p | MIMAT0004509 | MIRT038800 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-652-3p | MIMAT0003322 | MIRT039515 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-625-5p | MIMAT0003294 | MIRT039591 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039718 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-505-3p | MIMAT0002876 | MIRT040989 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-328-3p | MIMAT0000752 | MIRT043783 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-374a-5p | MIMAT0000727 | MIRT044015 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30b-5p | MIMAT0000420 | MIRT046130 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046390 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048435 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-27a-3p | MIMAT0000084 | MIRT050015 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-5p | MIMAT0000072 | MIRT050709 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051499 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052014 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-107 | MIMAT0000104 | NA | hsa-miR-107 | 17637574 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
