HCSGD entry for GAPVD1
1. General information
| Official gene symbol | GAPVD1 |
|---|---|
| Entrez ID | 26130 |
| Gene full name | GTPase activating protein and VPS9 domains 1 |
| Other gene symbols | GAPEX5 RAP6 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005085 | Guanyl-nucleotide exchange factor activity | IEA IMP | molecular_function |
| GO:0005096 | GTPase activator activity | IEA | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005768 | Endosome | IEA | cellular_component |
| GO:0005829 | Cytosol | IDA IEA | cellular_component |
| GO:0006897 | Endocytosis | IEA | biological_process |
| GO:0007165 | Signal transduction | IEA | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0032794 | GTPase activating protein binding | IEA IMP | molecular_function |
| GO:0043087 | Regulation of GTPase activity | IMP | biological_process |
| GO:0051056 | Regulation of small GTPase mediated signal transduction | IEA | biological_process |
| GO:0051223 | Regulation of protein transport | IEA IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0863096805 | 0.9365126287 | 0.6166865943 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0344689256 |
| GSE13712_SHEAR | Up | 0.0777920931 |
| GSE13712_STATIC | Up | 0.0938221621 |
| GSE19018 | Down | -0.1629939213 |
| GSE19899_A1 | Up | 0.4869975021 |
| GSE19899_A2 | Up | 0.2051369874 |
| PubMed_21979375_A1 | Up | 0.7386057971 |
| PubMed_21979375_A2 | Up | 0.5711697896 |
| GSE35957 | Up | 0.0087912761 |
| GSE36640 | Down | -0.2758070472 |
| GSE54402 | Up | 0.1681116736 |
| GSE9593 | Up | 0.1234157695 |
| GSE43922 | Up | 0.4112209735 |
| GSE24585 | Down | -0.0117919632 |
| GSE37065 | Up | 0.0386075888 |
| GSE28863_A1 | Up | 0.4650460321 |
| GSE28863_A2 | Up | 0.2903294228 |
| GSE28863_A3 | Down | -0.6092933579 |
| GSE28863_A4 | Down | -0.0163762095 |
| GSE48662 | Up | 0.0493714054 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020580 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025363 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027460 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030754 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032293 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047978 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
