HCSGD entry for SENP6
1. General information
| Official gene symbol | SENP6 |
|---|---|
| Entrez ID | 26054 |
| Gene full name | SUMO1/sentrin specific peptidase 6 |
| Other gene symbols | SSP1 SUSP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0008234 | Cysteine-type peptidase activity | IEA | molecular_function |
| GO:0016925 | Protein sumoylation | IEA | biological_process |
| GO:0016926 | Protein desumoylation | IMP | biological_process |
| GO:0016929 | SUMO-specific protease activity | IMP | molecular_function |
| GO:0070646 | Protein modification by small protein removal | IDA | biological_process |
| GO:0090169 | Regulation of spindle assembly | IMP | biological_process |
| GO:0090234 | Regulation of kinetochore assembly | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9676793435 | 0.0427503552 | 0.9999902473 | 0.3888330684 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2658787499 |
| GSE13712_SHEAR | Up | 0.1424653680 |
| GSE13712_STATIC | Down | -0.1982252294 |
| GSE19018 | Down | -0.1549401388 |
| GSE19899_A1 | Down | -0.1136642945 |
| GSE19899_A2 | Down | -0.5463690559 |
| PubMed_21979375_A1 | Up | 0.0270749650 |
| PubMed_21979375_A2 | Down | -0.7007872423 |
| GSE35957 | Up | 0.0028528951 |
| GSE36640 | Down | -0.3617162938 |
| GSE54402 | Down | -0.3636381663 |
| GSE9593 | Down | -0.1784120787 |
| GSE43922 | Down | -0.0024685837 |
| GSE24585 | Up | 0.1171634785 |
| GSE37065 | Down | -0.0260157543 |
| GSE28863_A1 | Up | 0.1883438396 |
| GSE28863_A2 | Up | 0.2680523082 |
| GSE28863_A3 | Down | -0.6141720168 |
| GSE28863_A4 | Down | -0.3878648168 |
| GSE48662 | Up | 0.0322151613 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT051074 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
