HCSGD entry for CNTNAP2

1. General information

Official gene symbolCNTNAP2
Entrez ID26047
Gene full namecontactin associated protein-like 2
Other gene symbolsAUTS15 CASPR2 CDFE NRXN4 PTHSL1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005769Early endosomeIDAcellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0007155Cell adhesionIEAbiological_process
GO:0007420Brain developmentTASbiological_process
GO:0007612LearningIMPbiological_process
GO:0008038Neuron recognitionNASbiological_process
GO:0008076Voltage-gated potassium channel complexIDAcellular_component
GO:0009986Cell surfaceIDAcellular_component
GO:0016020MembraneIDAcellular_component
GO:0016021Integral component of membraneIEA NAScellular_component
GO:0019226Transmission of nerve impulseNASbiological_process
GO:0019899Enzyme bindingIPImolecular_function
GO:0021756Striatum developmentIEPbiological_process
GO:0021761Limbic system developmentIEPbiological_process
GO:0021794Thalamus developmentIEPbiological_process
GO:0021987Cerebral cortex developmentIEPbiological_process
GO:0030424AxonISScellular_component
GO:0030425DendriteISScellular_component
GO:0030534Adult behaviorIMPbiological_process
GO:0030673AxolemmaIDAcellular_component
GO:0031175Neuron projection developmentIEA ISSbiological_process
GO:0034613Cellular protein localizationISSbiological_process
GO:0035176Social behaviorIMPbiological_process
GO:0043025Neuronal cell bodyISScellular_component
GO:0043204PerikaryonISScellular_component
GO:0044224Juxtaparanode region of axonIEA ISScellular_component
GO:0045163Clustering of voltage-gated potassium channelsISSbiological_process
GO:0071109Superior temporal gyrus developmentIEPbiological_process
GO:0071205Protein localization to juxtaparanode region of axonIEA ISSbiological_process
GO:0071625Vocalization behaviorIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.62433908290.72160943350.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1347065009
GSE13712_SHEARUp0.0817428578
GSE13712_STATICUp0.1279220088
GSE19018Down-0.0044277151
GSE19899_A1Up0.0647533378
GSE19899_A2Down-0.0341019227
PubMed_21979375_A1Down-0.0994098543
PubMed_21979375_A2Down-0.1262531190
GSE35957Up0.0901095703
GSE36640Up0.0675798926
GSE54402Down-0.0054562724
GSE9593Down-0.1363553200
GSE43922Up0.0144796337
GSE24585Down-0.3056168000
GSE37065Down-0.1913916548
GSE28863_A1Down-0.0343530818
GSE28863_A2Up0.3350497588
GSE28863_A3Up0.0808299812
GSE28863_A4Up0.0457150697
GSE48662Up0.3435313935

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-218-5pMIMAT0000275MIRT024222SequencingFunctional MTI (Weak)20371350
hsa-miR-99b-5pMIMAT0000689MIRT044172CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.