HCSGD entry for SIPA1L1

1. General information

Official gene symbolSIPA1L1
Entrez ID26037
Gene full namesignal-induced proliferation-associated 1 like 1
Other gene symbolsE6TP1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003674Molecular_functionNDmolecular_function
GO:0005096GTPase activator activityIEAmolecular_function
GO:0005575Cellular_componentNDcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0008150Biological_processNDbiological_process
GO:0014069Postsynaptic densityISScellular_component
GO:0030054Cell junctionIEAcellular_component
GO:0031532Actin cytoskeleton reorganizationISSbiological_process
GO:0032317Regulation of Rap GTPase activityIEA ISSbiological_process
GO:0032861Activation of Rap GTPase activityISSbiological_process
GO:0043197Dendritic spineISScellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0046875Ephrin receptor bindingIEAmolecular_function
GO:0048013Ephrin receptor signaling pathwayIEA ISSbiological_process
GO:0048167Regulation of synaptic plasticityISSbiological_process
GO:0050770Regulation of axonogenesisIEA ISSbiological_process
GO:0051056Regulation of small GTPase mediated signal transductionIEAbiological_process
GO:0061001Regulation of dendritic spine morphogenesisISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04094636980.44701833520.45340740431.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.6477917389
GSE13712_SHEARUp0.3527463328
GSE13712_STATICUp0.4695670937
GSE19018Down-0.6407234186
GSE19899_A1Up0.2483943212
GSE19899_A2Up0.9252538406
PubMed_21979375_A1Up0.7897107527
PubMed_21979375_A2Up0.7152081832
GSE35957Up0.2240144154
GSE36640Down-0.1813908923
GSE54402Up0.7144808732
GSE9593Up0.0462601266
GSE43922Up0.3904208893
GSE24585Up0.0498038752
GSE37065Up0.1331098435
GSE28863_A1Up0.1809003860
GSE28863_A2Down-0.3402036945
GSE28863_A3Down-0.4069567803
GSE28863_A4Down-0.0093036084
GSE48662Down-0.0520774330

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-92a-3pMIMAT0000092MIRT049597CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.