HCSGD entry for GLCE
1. General information
| Official gene symbol | GLCE |
|---|---|
| Entrez ID | 26035 |
| Gene full name | glucuronic acid epimerase |
| Other gene symbols | HSEPI |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IEA ISS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0006024 | Glycosaminoglycan biosynthetic process | IEA TAS | biological_process |
| GO:0015012 | Heparan sulfate proteoglycan biosynthetic process | IDA IEA ISS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016857 | Racemase and epimerase activity, acting on carbohydrates and derivatives | IEA ISS | molecular_function |
| GO:0030203 | Glycosaminoglycan metabolic process | TAS | biological_process |
| GO:0030210 | Heparin biosynthetic process | IEA ISS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0047464 | Heparosan-N-sulfate-glucuronate 5-epimerase activity | IMP | molecular_function |
| GO:0050379 | UDP-glucuronate 5'-epimerase activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0118690817 | 0.6196832187 | 0.2729114410 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0997389588 |
| GSE13712_SHEAR | Up | 0.0770890905 |
| GSE13712_STATIC | Up | 0.2892078905 |
| GSE19018 | Down | -0.9060034808 |
| GSE19899_A1 | Up | 2.2919579728 |
| GSE19899_A2 | Up | 0.5024308719 |
| PubMed_21979375_A1 | Up | 1.0755902045 |
| PubMed_21979375_A2 | Up | 1.0500647458 |
| GSE35957 | Down | -0.6519807973 |
| GSE36640 | Up | 0.1542422113 |
| GSE54402 | Up | 0.2984405804 |
| GSE9593 | Down | -0.1789475878 |
| GSE43922 | Up | 0.9961268206 |
| GSE24585 | Up | 0.4987877243 |
| GSE37065 | Up | 0.2935809739 |
| GSE28863_A1 | Up | 0.0114749583 |
| GSE28863_A2 | Up | 0.3066114483 |
| GSE28863_A3 | Down | -0.5207839729 |
| GSE28863_A4 | Up | 0.2601147711 |
| GSE48662 | Down | -0.6812525276 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30b-5p | MIMAT0000420 | MIRT023437 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-218-5p | MIMAT0000275 | MIRT024233 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-484 | MIMAT0002174 | MIRT042317 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
