HCSGD entry for UPF2
1. General information
| Official gene symbol | UPF2 |
|---|---|
| Entrez ID | 26019 |
| Gene full name | UPF2 regulator of nonsense transcripts homolog (yeast) |
| Other gene symbols | HUPF2 RENT2 smg-3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000184 | Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | IMP TAS | biological_process |
| GO:0001889 | Liver development | IEA | biological_process |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006406 | MRNA export from nucleus | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0016071 | MRNA metabolic process | TAS | biological_process |
| GO:0031100 | Organ regeneration | IEA | biological_process |
| GO:0035145 | Exon-exon junction complex | IDA | cellular_component |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0254112078 | 0.9672227081 | 0.3742634787 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2776316787 |
| GSE13712_SHEAR | Up | 0.7810338495 |
| GSE13712_STATIC | Up | 0.1649661220 |
| GSE19018 | Up | 0.0019586420 |
| GSE19899_A1 | Up | 0.5162912967 |
| GSE19899_A2 | Up | 0.1521855786 |
| PubMed_21979375_A1 | Up | 0.3827197732 |
| PubMed_21979375_A2 | Up | 0.7274122192 |
| GSE35957 | Down | -0.4875029455 |
| GSE36640 | Down | -0.1910860736 |
| GSE54402 | Up | 0.1252336217 |
| GSE9593 | Down | -0.2875320334 |
| GSE43922 | Up | 0.2249385504 |
| GSE24585 | Up | 0.0696753452 |
| GSE37065 | Up | 0.0739716275 |
| GSE28863_A1 | Up | 0.6874507642 |
| GSE28863_A2 | Up | 0.4677442596 |
| GSE28863_A3 | Down | -0.0023309086 |
| GSE28863_A4 | Up | 0.1903561809 |
| GSE48662 | Up | 0.0936720415 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020646 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020646 | Reporter assay;Other | Non-Functional MTI | 20584899 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049841 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
