HCSGD entry for ABP1

1. General information

Official gene symbolABP1
Entrez ID26
Gene full nameamiloride binding protein 1 (amine oxidase (copper-containing))
Other gene symbolsABP AOC1 DAO DAO1 KAO
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004872Receptor activityIDAmolecular_function
GO:0005261Cation channel activityIDAmolecular_function
GO:0005272Sodium channel activityTASmolecular_function
GO:0005507Copper ion bindingIDA IEAmolecular_function
GO:0005509Calcium ion bindingIDAmolecular_function
GO:0005615Extracellular spaceIDAcellular_component
GO:0005777PeroxisomeNAScellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005923Tight junctionISScellular_component
GO:0008131Primary amine oxidase activityIDA IEAmolecular_function
GO:0008144Drug bindingIDAmolecular_function
GO:0008201Heparin bindingIDAmolecular_function
GO:0008270Zinc ion bindingIDAmolecular_function
GO:0009308Amine metabolic processIEAbiological_process
GO:0032403Protein complex bindingIDAmolecular_function
GO:0035725Sodium ion transmembrane transportTASbiological_process
GO:0035874Cellular response to copper ion starvationIDAbiological_process
GO:0042493Response to drugIDAbiological_process
GO:0042803Protein homodimerization activityIPImolecular_function
GO:0046677Response to antibioticIDAbiological_process
GO:0048038Quinone bindingIDA IEAmolecular_function
GO:0052597Diamine oxidase activityIDAmolecular_function
GO:0052598Histamine oxidase activityIEAmolecular_function
GO:0052599Methylputrescine oxidase activityIEAmolecular_function
GO:0052600Propane-1,3-diamine oxidase activityIEAmolecular_function
GO:0055114Oxidation-reduction processIDAbiological_process
GO:0071280Cellular response to copper ionIDAbiological_process
GO:0071420Cellular response to histamineIDAbiological_process
GO:0071504Cellular response to heparinTASbiological_process
GO:0097185Cellular response to azideIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.52753345620.92389808520.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0656577207
GSE13712_SHEARUp0.1483691610
GSE13712_STATICUp0.0763584764
GSE19018Up0.1098446943
GSE19899_A1Up0.0050287919
GSE19899_A2Up0.0642407996
PubMed_21979375_A1Down-0.0298452610
PubMed_21979375_A2Up0.1457133548
GSE35957Up0.1750528581
GSE36640Up0.1436819437
GSE54402Up0.0179070894
GSE9593Up0.1598241899
GSE43922Up0.0255676777
GSE24585Down-0.0646212056
GSE37065Up0.0835007640
GSE28863_A1Down-0.0807568059
GSE28863_A2Up0.1275897568
GSE28863_A3Up0.0600631104
GSE28863_A4Up0.0726353029
GSE48662Up0.0163305522

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

AmilorideDB00594 APRD00790 | EXPT00514
DiminazeneDB03608 EXPT00754

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.