HCSGD entry for REXO2
1. General information
| Official gene symbol | REXO2 |
|---|---|
| Entrez ID | 25996 |
| Gene full name | REX2, RNA exonuclease 2 homolog (S. cerevisiae) |
| Other gene symbols | REX2 RFN SFN |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0004527 | Exonuclease activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006139 | Nucleobase-containing compound metabolic process | IDA | biological_process |
| GO:0008408 | 3'-5' exonuclease activity | IDA | molecular_function |
| GO:0009117 | Nucleotide metabolic process | TAS | biological_process |
| GO:0090305 | Nucleic acid phosphodiester bond hydrolysis | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7816881653 | 0.1849369781 | 0.9999902473 | 0.8336575098 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1222074538 |
| GSE13712_SHEAR | Up | 0.0801571987 |
| GSE13712_STATIC | Down | -0.0169603947 |
| GSE19018 | Up | 0.4180656409 |
| GSE19899_A1 | Down | -0.1822132982 |
| GSE19899_A2 | Down | -0.0837025955 |
| PubMed_21979375_A1 | Down | -0.7080280872 |
| PubMed_21979375_A2 | Down | -0.1957715038 |
| GSE35957 | Up | 0.0479892325 |
| GSE36640 | Up | 0.0824775088 |
| GSE54402 | Down | -0.4272382388 |
| GSE9593 | Up | 0.3114867999 |
| GSE43922 | Down | -0.1256625536 |
| GSE24585 | Down | -0.3531893105 |
| GSE37065 | Down | -0.3261553543 |
| GSE28863_A1 | Up | 0.1737437780 |
| GSE28863_A2 | Up | 0.4731476701 |
| GSE28863_A3 | Down | -0.1896329319 |
| GSE28863_A4 | Up | 0.1240812653 |
| GSE48662 | Down | -0.0087735497 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1229-3p | MIMAT0005584 | MIRT036305 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040651 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047931 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
