HCSGD entry for CHMP2B
1. General information
| Official gene symbol | CHMP2B |
|---|---|
| Entrez ID | 25978 |
| Gene full name | charged multivesicular body protein 2B |
| Other gene symbols | ALS17 CHMP2.5 DMT1 VPS2-2 VPS2B |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005622 | Intracellular | IDA | cellular_component |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0016197 | Endosomal transport | TAS | biological_process |
| GO:0019904 | Protein domain specific binding | IPI | molecular_function |
| GO:0031902 | Late endosome membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9557426694 | 0.0429479693 | 0.9999902473 | 0.3900736715 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0712133141 |
| GSE13712_SHEAR | Down | -0.5972281102 |
| GSE13712_STATIC | Up | 0.1224133793 |
| GSE19018 | Down | -0.1507284921 |
| GSE19899_A1 | Down | -0.3108954478 |
| GSE19899_A2 | Down | -0.1515757612 |
| PubMed_21979375_A1 | Down | -0.0831094257 |
| PubMed_21979375_A2 | Down | -0.1657484567 |
| GSE35957 | Up | 0.2810348040 |
| GSE36640 | Down | -0.0384877398 |
| GSE54402 | Down | -0.1668667107 |
| GSE9593 | Up | 0.3748545384 |
| GSE43922 | Down | -0.1632728078 |
| GSE24585 | Down | -0.0512086434 |
| GSE37065 | Up | 0.2201547540 |
| GSE28863_A1 | Down | -0.4565324237 |
| GSE28863_A2 | Up | 0.0371852182 |
| GSE28863_A3 | Down | -0.4934400237 |
| GSE28863_A4 | Down | -0.3998179195 |
| GSE48662 | Down | -0.5097348401 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-9-5p | MIMAT0000441 | MIRT021402 | Western blot;qRT-PCR | Functional MTI | 20362537 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022727 | qRT-PCR | Non-Functional MTI (Weak) | 20362537 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
