HCSGD entry for KANK2
1. General information
| Official gene symbol | KANK2 |
|---|---|
| Entrez ID | 25959 |
| Gene full name | KN motif and ankyrin repeat domains 2 |
| Other gene symbols | ANKRD25 MXRA3 SIP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0008285 | Negative regulation of cell proliferation | IDA | biological_process |
| GO:0033147 | Negative regulation of intracellular estrogen receptor signaling pathway | IDA | biological_process |
| GO:0043069 | Negative regulation of programmed cell death | IDA | biological_process |
| GO:2000134 | Negative regulation of G1/S transition of mitotic cell cycle | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2206109000 | 0.2813810911 | 0.9019175229 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1117346224 |
| GSE13712_SHEAR | Up | 0.2516837413 |
| GSE13712_STATIC | Up | 0.1962658183 |
| GSE19018 | Down | -0.2922130858 |
| GSE19899_A1 | Down | -0.5046318860 |
| GSE19899_A2 | Down | -0.3281085192 |
| PubMed_21979375_A1 | Down | -0.7449619855 |
| PubMed_21979375_A2 | Down | -0.1665473930 |
| GSE35957 | Up | 0.0872145979 |
| GSE36640 | Down | -0.0022687908 |
| GSE54402 | Down | -0.0226861935 |
| GSE9593 | Up | 0.0822879803 |
| GSE43922 | Down | -0.1819568179 |
| GSE24585 | Up | 0.5433636385 |
| GSE37065 | Down | -0.1668790929 |
| GSE28863_A1 | Up | 1.0374715584 |
| GSE28863_A2 | Up | 0.7036531149 |
| GSE28863_A3 | Up | 0.3939698066 |
| GSE28863_A4 | Down | -0.0110018323 |
| GSE48662 | Down | -0.1840443548 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016547 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020755 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022589 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT023699 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029311 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT044246 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049313 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
