HCSGD entry for NSL1


1. General information

Official gene symbolNSL1
Entrez ID25936
Gene full nameNSL1, MIND kinetochore complex component, homolog (S. cerevisiae)
Other gene symbolsC1orf48 MIS14
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000278Mitotic cell cycleTASbiological_process
GO:0000444MIS12/MIND type complexIDAcellular_component
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0007059Chromosome segregationIEAbiological_process
GO:0007067MitosisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97892110480.02021410280.99999024730.2753909938

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0537060886
GSE13712_SHEARDown-0.2152631501
GSE13712_STATICUp0.0716055557
GSE19018Down-0.2058596612
GSE19899_A1Down-0.3265184480
GSE19899_A2Down-1.0112589742
PubMed_21979375_A1Down-0.7922930121
PubMed_21979375_A2Down-1.4100200175
GSE35957Down-0.2822891886
GSE36640Down-0.6996110585
GSE54402Down-0.3102016540
GSE9593Down-0.2183269005
GSE43922Down-0.4932789434
GSE24585Up0.2687468120
GSE37065Up0.1700566260
GSE28863_A1Up0.0799384541
GSE28863_A2Up0.4047251412
GSE28863_A3Down-0.3795869470
GSE28863_A4Down-0.0764776124
GSE48662Down-0.3187760939

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-421MIMAT0003339MIRT016100SequencingFunctional MTI (Weak)20371350
hsa-miR-26b-5pMIMAT0000083MIRT030278MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.