HCSGD entry for PTPN23
1. General information
| Official gene symbol | PTPN23 |
|---|---|
| Entrez ID | 25930 |
| Gene full name | protein tyrosine phosphatase, non-receptor type 23 |
| Other gene symbols | HD-PTP HDPTP PTP-TD14 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004725 | Protein tyrosine phosphatase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005768 | Endosome | IDA | cellular_component |
| GO:0005769 | Early endosome | IDA | cellular_component |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016023 | Cytoplasmic membrane-bounded vesicle | IEA | cellular_component |
| GO:0036064 | Ciliary basal body | IDA | cellular_component |
| GO:0043162 | Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway | IMP | biological_process |
| GO:0060271 | Cilium morphogenesis | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1349332700 | 0.9131743323 | 0.7433389597 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1098120082 |
| GSE13712_SHEAR | Up | 0.0530211893 |
| GSE13712_STATIC | Down | -0.1291453996 |
| GSE19018 | Up | 0.0575406428 |
| GSE19899_A1 | Down | -0.1226357059 |
| GSE19899_A2 | Down | -0.0016971978 |
| PubMed_21979375_A1 | Up | 0.2833594755 |
| PubMed_21979375_A2 | Up | 0.7395372683 |
| GSE35957 | Down | -0.0516203195 |
| GSE36640 | Up | 0.0329728711 |
| GSE54402 | Up | 0.0797254343 |
| GSE9593 | Up | 0.2643806275 |
| GSE43922 | Up | 0.0519863892 |
| GSE24585 | Up | 0.0834776880 |
| GSE37065 | Down | -0.1390520252 |
| GSE28863_A1 | Up | 0.3537000144 |
| GSE28863_A2 | Up | 0.4089831628 |
| GSE28863_A3 | Up | 0.1659864676 |
| GSE28863_A4 | Down | -0.0545589159 |
| GSE48662 | Up | 0.1945137352 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-148a-3p | MIMAT0000243 | MIRT048027 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050524 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT051946 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
