HCSGD entry for SOSTDC1


1. General information

Official gene symbolSOSTDC1
Entrez ID25928
Gene full namesclerostin domain containing 1
Other gene symbolsECTODIN USAG1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005615Extracellular spaceIEAcellular_component
GO:0007389Pattern specification processIEAbiological_process
GO:0010454Negative regulation of cell fate commitmentIEAbiological_process
GO:0016055Wnt signaling pathwayIEAbiological_process
GO:0030514Negative regulation of BMP signaling pathwayIEAbiological_process
GO:0031069Hair follicle morphogenesisIEAbiological_process
GO:0042475Odontogenesis of dentin-containing toothIEAbiological_process
GO:0060648Mammary gland bud morphogenesisIEAbiological_process
GO:0090090Negative regulation of canonical Wnt signaling pathwayIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.65432510160.67361061890.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0649309951
GSE13712_SHEARDown-0.1477913403
GSE13712_STATICDown-0.0102969489
GSE19018Down-0.0436150975
GSE19899_A1Down-0.1070481826
GSE19899_A2Down-0.2454478678
PubMed_21979375_A1Up0.0838266506
PubMed_21979375_A2Down-0.1208262118
GSE35957Up0.1413161108
GSE36640Up0.0235633588
GSE54402Up0.0800788307
GSE9593Down-0.2745333672
GSE43922Up0.1365556044
GSE24585Up0.5712477313
GSE37065Up0.1130012351
GSE28863_A1Up0.0620965323
GSE28863_A2Up0.0533981855
GSE28863_A3Up0.0733037005
GSE28863_A4Down-0.1126876689
GSE48662Down-0.0595668494

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018039MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.