HCSGD entry for ASPM
1. General information
| Official gene symbol | ASPM |
|---|---|
| Entrez ID | 259266 |
| Gene full name | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| Other gene symbols | ASP Calmbp1 MCPH5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000922 | Spindle pole | IEA | cellular_component |
| GO:0001764 | Neuron migration | IEA | biological_process |
| GO:0002052 | Positive regulation of neuroblast proliferation | IEA | biological_process |
| GO:0005516 | Calmodulin binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0007283 | Spermatogenesis | IEA | biological_process |
| GO:0021873 | Forebrain neuroblast division | IEA | biological_process |
| GO:0030496 | Midbody | IEA | cellular_component |
| GO:0045665 | Negative regulation of neuron differentiation | IEA | biological_process |
| GO:0045769 | Negative regulation of asymmetric cell division | IEA | biological_process |
| GO:0048477 | Oogenesis | IEA | biological_process |
| GO:0048589 | Developmental growth | IEA | biological_process |
| GO:0051661 | Maintenance of centrosome location | IEA | biological_process |
| GO:0090263 | Positive regulation of canonical Wnt signaling pathway | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6857601497 | 0.0000111432 | 0.9999902473 | 0.0069833333 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.8790160244 |
| GSE13712_SHEAR | Down | -0.4086613887 |
| GSE13712_STATIC | Down | -0.5525883493 |
| GSE19018 | Up | 0.4795171594 |
| GSE19899_A1 | Down | -1.1218410751 |
| GSE19899_A2 | Down | -4.3625983142 |
| PubMed_21979375_A1 | Down | -4.8254462881 |
| PubMed_21979375_A2 | Down | -3.7789889873 |
| GSE35957 | Down | -2.6985771965 |
| GSE36640 | Down | -5.5853768438 |
| GSE54402 | Down | -1.5141257447 |
| GSE9593 | Down | -1.3430293981 |
| GSE43922 | Down | -3.6619307068 |
| GSE24585 | Down | -0.0162165059 |
| GSE37065 | Down | -1.2396297639 |
| GSE28863_A1 | Up | 0.2382590656 |
| GSE28863_A2 | Up | 2.2573887248 |
| GSE28863_A3 | Down | -0.3911075742 |
| GSE28863_A4 | Up | 0.1799192759 |
| GSE48662 | Down | -2.1331873838 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016478 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024686 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026460 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029549 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052495 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
