HCSGD entry for NELFB
1. General information
| Official gene symbol | NELFB |
|---|---|
| Entrez ID | 25920 |
| Gene full name | negative elongation factor complex member B |
| Other gene symbols | COBRA1 NELF-B |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006368 | Transcription elongation from RNA polymerase II promoter | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0032021 | NELF complex | IDA | cellular_component |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0050434 | Positive regulation of viral transcription | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5509326165 | 0.1456440713 | 0.9999902473 | 0.7364342808 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0098336715 |
| GSE13712_SHEAR | Down | -0.1364975925 |
| GSE13712_STATIC | Up | 0.0233991174 |
| GSE19018 | Up | 0.3741073306 |
| GSE19899_A1 | Up | 0.0015833804 |
| GSE19899_A2 | Up | 0.2104016463 |
| PubMed_21979375_A1 | Down | -0.1094259709 |
| PubMed_21979375_A2 | Up | 0.8420652282 |
| GSE35957 | Down | -0.3628203506 |
| GSE36640 | Down | -0.6763271033 |
| GSE54402 | Up | 0.0454540702 |
| GSE9593 | Down | -0.5290114723 |
| GSE43922 | Up | 0.2016448955 |
| GSE24585 | Down | -0.3562820141 |
| GSE37065 | Down | -0.2279197694 |
| GSE28863_A1 | Up | 0.1327866692 |
| GSE28863_A2 | Down | -0.0732818524 |
| GSE28863_A3 | Down | -0.5177164410 |
| GSE28863_A4 | Down | -0.2008017011 |
| GSE48662 | Up | 0.3460334926 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-324-5p | MIMAT0000761 | MIRT043077 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045525 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
