HCSGD entry for RCHY1

1. General information

Official gene symbolRCHY1
Entrez ID25898
Gene full namering finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
Other gene symbolsARNIP CHIMP PIRH2 PIRH2E PIRH2F PRO1996 RNF199 ZNF363 hARNIP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000151Ubiquitin ligase complexIDAcellular_component
GO:0002039P53 bindingIPImolecular_function
GO:0004842Ubiquitin-protein ligase activityIDAmolecular_function
GO:0005102Receptor bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0008270Zinc ion bindingIDA IEAmolecular_function
GO:0016567Protein ubiquitinationIDAbiological_process
GO:0016607Nuclear speckIEAcellular_component
GO:0031398Positive regulation of protein ubiquitinationIDAbiological_process
GO:0032436Positive regulation of proteasomal ubiquitin-dependent protein catabolic processIDAbiological_process
GO:0042787Protein ubiquitination involved in ubiquitin-dependent protein catabolic processIDAbiological_process
GO:0042803Protein homodimerization activityIPImolecular_function
GO:0051865Protein autoubiquitinationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.16645189390.55564507430.80586284721.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1294728157
GSE13712_SHEARDown-0.0580418115
GSE13712_STATICUp0.0382086791
GSE19018Down-0.2652241742
GSE19899_A1Up0.5294303210
GSE19899_A2Up0.7048380260
PubMed_21979375_A1Up0.7378022354
PubMed_21979375_A2Up0.8644654374
GSE35957Up0.0078883253
GSE36640Up0.1312992923
GSE54402Down-0.0623154415
GSE9593Down-0.2221671261
GSE43922Up0.4939187652
GSE24585Up0.0317587250
GSE37065Down-0.0038398817
GSE28863_A1Down-0.2464040152
GSE28863_A2Down-0.2820164494
GSE28863_A3Down-0.2424624968
GSE28863_A4Down-0.0848343629
GSE48662Down-0.2863083887

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.