HCSGD entry for GALK1
1. General information
| Official gene symbol | GALK1 |
|---|---|
| Entrez ID | 2584 |
| Gene full name | galactokinase 1 |
| Other gene symbols | GALK GK1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004335 | Galactokinase activity | IDA IEA | molecular_function |
| GO:0005524 | ATP binding | IDA IEA | molecular_function |
| GO:0005534 | Galactose binding | IDA | molecular_function |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0006012 | Galactose metabolic process | IEA IMP | biological_process |
| GO:0016020 | Membrane | IDA | cellular_component |
| GO:0019388 | Galactose catabolic process | TAS | biological_process |
| GO:0019402 | Galactitol metabolic process | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8706195509 | 0.1133885529 | 0.9999902473 | 0.6454368728 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2013713099 |
| GSE13712_SHEAR | Down | -0.0147487390 |
| GSE13712_STATIC | Up | 0.4130694810 |
| GSE19018 | Up | 0.2696670987 |
| GSE19899_A1 | Down | -0.2875104585 |
| GSE19899_A2 | Down | -0.1343489620 |
| PubMed_21979375_A1 | Down | -0.0757503656 |
| PubMed_21979375_A2 | Down | -0.4862984868 |
| GSE35957 | Down | -0.2454993269 |
| GSE36640 | Down | -0.2810487790 |
| GSE54402 | Down | -0.1847738605 |
| GSE9593 | Down | -0.0059368653 |
| GSE43922 | Down | -0.2066226367 |
| GSE24585 | Up | 0.2183385536 |
| GSE37065 | Down | -0.1398000259 |
| GSE28863_A1 | Down | -0.0148129084 |
| GSE28863_A2 | Down | -0.2848769093 |
| GSE28863_A3 | Up | 0.0932588934 |
| GSE28863_A4 | Up | 0.0141627380 |
| GSE48662 | Up | 0.0811263456 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Phosphoaminophosphonic Acid-Adenylate Ester | DB04395 | EXPT00524 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029752 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-1225-5p | MIMAT0005572 | MIRT036546 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040306 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
