HCSGD entry for POU2F3
1. General information
| Official gene symbol | POU2F3 |
|---|---|
| Entrez ID | 25833 |
| Gene full name | POU class 2 homeobox 3 |
| Other gene symbols | Epoc-1 OCT-11 OCT11 OTF-11 PLA-1 PLA1 Skn-1a |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005667 | Transcription factor complex | IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0008544 | Epidermis development | TAS | biological_process |
| GO:0030216 | Keratinocyte differentiation | IEA | biological_process |
| GO:0042060 | Wound healing | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IDA | molecular_function |
| GO:0043922 | Negative regulation by host of viral transcription | IDA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0046983 | Protein dimerization activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6654076821 | 0.8866610843 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0500231299 |
| GSE13712_SHEAR | Down | -0.0467492179 |
| GSE13712_STATIC | Up | 0.0523511096 |
| GSE19018 | Down | -0.0864518365 |
| GSE19899_A1 | Up | 0.0480306764 |
| GSE19899_A2 | Down | -0.0369448325 |
| PubMed_21979375_A1 | Up | 0.2550010360 |
| PubMed_21979375_A2 | Down | -0.0284091954 |
| GSE35957 | Up | 0.1427201876 |
| GSE36640 | Down | -0.0487708064 |
| GSE54402 | Up | 0.0547241773 |
| GSE9593 | Down | -0.0017636539 |
| GSE43922 | Up | 0.0458553273 |
| GSE24585 | Up | 0.0688663426 |
| GSE37065 | Down | -0.0251001537 |
| GSE28863_A1 | Up | 0.0025795671 |
| GSE28863_A2 | Down | -0.0247286191 |
| GSE28863_A3 | Up | 0.2333353234 |
| GSE28863_A4 | Up | 0.1390673501 |
| GSE48662 | Up | 0.0375256466 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016830 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028932 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
