HCSGD entry for TXN2
1. General information
| Official gene symbol | TXN2 |
|---|---|
| Entrez ID | 25828 |
| Gene full name | thioredoxin 2 |
| Other gene symbols | MT-TRX MTRX TRX2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001666 | Response to hypoxia | IEA | biological_process |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA IEA | cellular_component |
| GO:0006662 | Glycerol ether metabolic process | IEA | biological_process |
| GO:0006979 | Response to oxidative stress | IEA | biological_process |
| GO:0007584 | Response to nutrient | IEA | biological_process |
| GO:0009725 | Response to hormone | IEA | biological_process |
| GO:0009749 | Response to glucose | IEA | biological_process |
| GO:0014070 | Response to organic cyclic compound | IEA | biological_process |
| GO:0015035 | Protein disulfide oxidoreductase activity | IEA | molecular_function |
| GO:0030425 | Dendrite | IEA | cellular_component |
| GO:0031669 | Cellular response to nutrient levels | IEA | biological_process |
| GO:0032403 | Protein complex binding | IEA | molecular_function |
| GO:0042493 | Response to drug | IEA | biological_process |
| GO:0043025 | Neuronal cell body | IEA | cellular_component |
| GO:0045454 | Cell redox homeostasis | IEA | biological_process |
| GO:0048678 | Response to axon injury | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1507451655 | 0.5930273698 | 0.7757407038 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4025342084 |
| GSE13712_SHEAR | Down | -0.0046040294 |
| GSE13712_STATIC | Up | 0.0629599981 |
| GSE19018 | Down | -0.0483261062 |
| GSE19899_A1 | Up | 0.0726586576 |
| GSE19899_A2 | Up | 0.5843922753 |
| PubMed_21979375_A1 | Up | 1.1805958643 |
| PubMed_21979375_A2 | Up | 0.2349674957 |
| GSE35957 | Down | -0.4743379823 |
| GSE36640 | Down | -0.0115934678 |
| GSE54402 | Up | 0.0894535835 |
| GSE9593 | Down | -0.2204574373 |
| GSE43922 | Up | 0.2099576696 |
| GSE24585 | Up | 0.3341954909 |
| GSE37065 | Down | -0.2236798229 |
| GSE28863_A1 | Up | 0.0325659806 |
| GSE28863_A2 | Down | -0.5485561182 |
| GSE28863_A3 | Down | -0.4718450866 |
| GSE28863_A4 | Up | 0.1590953758 |
| GSE48662 | Up | 0.0962952205 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT001402 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-877-5p | MIMAT0004949 | MIRT037320 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-296-3p | MIMAT0004679 | MIRT038474 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-425-5p | MIMAT0003393 | MIRT039307 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT044903 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
