HCSGD entry for MTO1


1. General information

Official gene symbolMTO1
Entrez ID25821
Gene full namemitochondrial tRNA translation optimization 1
Other gene symbolsCOXPD10
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005739MitochondrionIEAcellular_component
GO:0008033TRNA processingIEAbiological_process
GO:0050660Flavin adenine dinucleotide bindingIEAmolecular_function
GO:0055114Oxidation-reduction processIEAbiological_process
GO:0070899Mitochondrial tRNA wobble uridine modificationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.07513163250.79048354170.58077524231.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3340643195
GSE13712_SHEARUp0.1014103490
GSE13712_STATICUp0.1819020168
GSE19018Down-0.1875393858
GSE19899_A1Up0.3894507559
GSE19899_A2Up0.4607187875
PubMed_21979375_A1Up0.9125218273
PubMed_21979375_A2Up0.2145174156
GSE35957Down-0.2012972595
GSE36640Down-0.1241705695
GSE54402Up0.1173998497
GSE9593Down-0.1468973323
GSE43922Up0.2679620768
GSE24585Up0.2212526900
GSE37065Down-0.1131525759
GSE28863_A1Up0.4345570777
GSE28863_A2Up0.5217160671
GSE28863_A3Down-0.3630178189
GSE28863_A4Down-0.2628990658
GSE48662Down-0.3546789334

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-100-5pMIMAT0000098MIRT048594CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.