HCSGD entry for CCRN4L
1. General information
| Official gene symbol | CCRN4L |
|---|---|
| Entrez ID | 25819 |
| Gene full name | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| Other gene symbols | CCR4L NOC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000290 | Deadenylation-dependent decapping of nuclear-transcribed mRNA | IEA | biological_process |
| GO:0000932 | Cytoplasmic mRNA processing body | IEA | cellular_component |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | TAS | molecular_function |
| GO:0004535 | Poly(A)-specific ribonuclease activity | IEA | molecular_function |
| GO:0005634 | Nucleus | TAS | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0006355 | Regulation of transcription, DNA-templated | TAS | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0033962 | Cytoplasmic mRNA processing body assembly | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0048511 | Rhythmic process | IEA | biological_process |
| GO:2001141 | Regulation of RNA biosynthetic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0118720261 | 0.8445192660 | 0.2729114410 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1310777760 |
| GSE13712_SHEAR | Up | 1.0060780035 |
| GSE13712_STATIC | Up | 0.7001438579 |
| GSE19018 | Up | 0.1822649113 |
| GSE19899_A1 | Up | 0.4172935489 |
| GSE19899_A2 | Up | 1.2134053603 |
| PubMed_21979375_A1 | Up | 2.2825386689 |
| PubMed_21979375_A2 | Up | 0.8887686758 |
| GSE35957 | Down | -0.4729824683 |
| GSE36640 | Up | 0.0598214360 |
| GSE54402 | Up | 0.7629805012 |
| GSE9593 | Down | -0.3906043091 |
| GSE43922 | Up | 0.7194446650 |
| GSE24585 | Down | -0.0141234263 |
| GSE37065 | Down | -0.1935977261 |
| GSE28863_A1 | Down | -0.1290015423 |
| GSE28863_A2 | Down | -0.0355445749 |
| GSE28863_A3 | Down | -0.0701529909 |
| GSE28863_A4 | Down | -0.1350070892 |
| GSE48662 | Up | 0.1280420967 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-296-3p | MIMAT0004679 | MIRT038417 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051636 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 21605287 | However, rDNA may also act as a NOC with respect to cellular senescence by limiting the number of times a cell can divide |
| 21605287 | Here, I discuss how rDNA might function as a NOC to influence life span in a manner analogous to telomeres |
| 20890120 | In this Extra View we discuss the interactive role of three molecules, PPARgamma, nocturnin and IGF-I in regulating stem cell fate in the marrow and the potential implications of this network for understanding cellular aging |
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