HCSGD entry for TTLL1


1. General information

Official gene symbolTTLL1
Entrez ID25809
Gene full nametubulin tyrosine ligase-like family, member 1
Other gene symbolsC22orf7 HS323M22B
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003351Epithelial cilium movementIEAbiological_process
GO:0005737CytoplasmIEAcellular_component
GO:0005874MicrotubuleIEAcellular_component
GO:0018095Protein polyglutamylationTASbiological_process
GO:0044782Cilium organizationIEAbiological_process
GO:0060271Cilium morphogenesisIEAbiological_process
GO:0070740Tubulin-glutamic acid ligase activityTASmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.63175375180.04891520460.99999024730.4135940893

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0034151910
GSE13712_SHEARDown-0.4769348952
GSE13712_STATICDown-0.0987525152
GSE19018Up0.2930686580
GSE19899_A1Down-0.3688419241
GSE19899_A2Down-0.5362144736
PubMed_21979375_A1Down-0.8328436711
PubMed_21979375_A2Down-0.5089849316
GSE35957Down-0.3652526030
GSE36640Up0.6263187835
GSE54402Down-0.1724401808
GSE9593Up0.4201670739
GSE43922Down-0.7376145186
GSE24585Up0.8856513422
GSE37065Down-0.2768904491
GSE28863_A1Down-0.1619778837
GSE28863_A2Down-0.2376003059
GSE28863_A3Down-0.1810500798
GSE28863_A4Up0.1437521664
GSE48662Up0.0953905762

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017600MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.