HCSGD entry for VAX2

1. General information

Official gene symbolVAX2
Entrez ID25806
Gene full nameventral anterior homeobox 2
Other gene symbolsDRES93
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0000976Transcription regulatory region sequence-specific DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007398Ectoderm developmentTASbiological_process
GO:0007409AxonogenesisIEAbiological_process
GO:0007601Visual perceptionTASbiological_process
GO:0009950Dorsal/ventral axis specificationIEAbiological_process
GO:0016055Wnt signaling pathwayIEAbiological_process
GO:0030900Forebrain developmentISSbiological_process
GO:0031490Chromatin DNA bindingIEAmolecular_function
GO:0048048Embryonic eye morphogenesisIEAbiological_process
GO:0060041Retina development in camera-type eyeIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.22034819730.95308199540.90191752291.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0011854710
GSE13712_SHEARDown-0.0749495685
GSE13712_STATICDown-0.1478078375
GSE19018Up0.1314913705
GSE19899_A1Up0.0341673548
GSE19899_A2Up0.5150495111
PubMed_21979375_A1Up0.7195967809
PubMed_21979375_A2Up0.0512772731
GSE35957Down-0.0124269588
GSE36640Up0.1861094356
GSE54402Up0.1192542238
GSE9593Up0.2353766247
GSE43922Up0.0832963295
GSE24585Up0.0218761152
GSE37065Down-0.0978191657
GSE28863_A1Down-0.0396871339
GSE28863_A2Up0.0401498936
GSE28863_A3Up0.3895149708
GSE28863_A4Up0.0660534715
GSE48662Up0.2281308597

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.