HCSGD entry for LSM4
1. General information
| Official gene symbol | LSM4 |
|---|---|
| Entrez ID | 25804 |
| Gene full name | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| Other gene symbols | GRP YER112W |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000288 | Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | TAS | biological_process |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005681 | Spliceosomal complex | IEA | cellular_component |
| GO:0005688 | U6 snRNP | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0008380 | RNA splicing | IEA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0016071 | MRNA metabolic process | TAS | biological_process |
| GO:0030532 | Small nuclear ribonucleoprotein complex | TAS | cellular_component |
| GO:0043928 | Exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5312732153 | 0.2217213708 | 0.9999902473 | 0.9055109232 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0926518120 |
| GSE13712_SHEAR | Down | -0.2293263681 |
| GSE13712_STATIC | Down | -0.1240506389 |
| GSE19018 | Up | 0.4109036267 |
| GSE19899_A1 | Down | -0.1382697637 |
| GSE19899_A2 | Up | 0.0459021042 |
| PubMed_21979375_A1 | Down | -0.0025269030 |
| PubMed_21979375_A2 | Down | -0.7502980335 |
| GSE35957 | Down | -0.0806722688 |
| GSE36640 | Down | -0.3086791812 |
| GSE54402 | Up | 0.1372279520 |
| GSE9593 | Down | -0.1622071205 |
| GSE43922 | Down | -0.0400467061 |
| GSE24585 | Down | -0.4445323127 |
| GSE37065 | Down | -0.2215113389 |
| GSE28863_A1 | Down | -0.1161234833 |
| GSE28863_A2 | Up | 0.1284578665 |
| GSE28863_A3 | Up | 0.3404634758 |
| GSE28863_A4 | Up | 0.2815857790 |
| GSE48662 | Up | 0.0925600460 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-769-5p | MIMAT0003886 | MIRT039176 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042595 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
