HCSGD entry for GAK
1. General information
| Official gene symbol | GAK |
|---|---|
| Entrez ID | 2580 |
| Gene full name | cyclin G associated kinase |
| Other gene symbols | DNAJ26 DNAJC26 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004672 | Protein kinase activity | IEA | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005925 | Focal adhesion | IEA | cellular_component |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0016301 | Kinase activity | IEA | molecular_function |
| GO:0016772 | Transferase activity, transferring phosphorus-containing groups | IEA | molecular_function |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0187643669 | 0.9904727594 | 0.3350725237 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5033399010 |
| GSE13712_SHEAR | Up | 0.1075170734 |
| GSE13712_STATIC | Up | 0.0631943525 |
| GSE19018 | Up | 0.0023207460 |
| GSE19899_A1 | Up | 0.1987213253 |
| GSE19899_A2 | Up | 0.8747080678 |
| PubMed_21979375_A1 | Up | 1.3745687194 |
| PubMed_21979375_A2 | Up | 1.2864970183 |
| GSE35957 | Up | 0.0789791322 |
| GSE36640 | Up | 0.1215448212 |
| GSE54402 | Up | 0.7645546232 |
| GSE9593 | Up | 0.0025289109 |
| GSE43922 | Up | 0.4514178368 |
| GSE24585 | Up | 0.0372306532 |
| GSE37065 | Up | 0.0599735377 |
| GSE28863_A1 | Up | 0.0818955354 |
| GSE28863_A2 | Up | 0.0295398273 |
| GSE28863_A3 | Up | 0.1153170245 |
| GSE28863_A4 | Down | -0.1054350974 |
| GSE48662 | Up | 0.1781706287 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT001367 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037433 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-301a-3p | MIMAT0000688 | MIRT044214 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049506 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
