HCSGD entry for FBXO7
1. General information
| Official gene symbol | FBXO7 |
|---|---|
| Entrez ID | 25793 |
| Gene full name | F-box protein 7 |
| Other gene symbols | FBX FBX07 FBX7 PARK15 PKPS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000151 | Ubiquitin ligase complex | TAS | cellular_component |
| GO:0004842 | Ubiquitin-protein ligase activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | TAS | biological_process |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0031647 | Regulation of protein stability | IDA | biological_process |
| GO:0043234 | Protein complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8322006383 | 0.5110242772 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2620968444 |
| GSE13712_SHEAR | Down | -0.0417070873 |
| GSE13712_STATIC | Down | -0.0964399180 |
| GSE19018 | Up | 0.0633239051 |
| GSE19899_A1 | Down | -0.0948600421 |
| GSE19899_A2 | Up | 0.0753326348 |
| PubMed_21979375_A1 | Down | -0.3061752536 |
| PubMed_21979375_A2 | Down | -0.0482890558 |
| GSE35957 | Down | -0.3224548609 |
| GSE36640 | Down | -0.0342699183 |
| GSE54402 | Up | 0.0246619035 |
| GSE9593 | Up | 0.0475933247 |
| GSE43922 | Down | -0.0043515718 |
| GSE24585 | Up | 0.1374987658 |
| GSE37065 | Up | 0.1797969723 |
| GSE28863_A1 | Up | 0.0077797481 |
| GSE28863_A2 | Up | 0.0355027484 |
| GSE28863_A3 | Down | -0.6530815022 |
| GSE28863_A4 | Up | 0.1357832367 |
| GSE48662 | Down | -0.0497358261 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-122-5p | MIMAT0000421 | MIRT023257 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-877-5p | MIMAT0004949 | MIRT037372 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
