HCSGD entry for NPNT

1. General information

Official gene symbolNPNT
Entrez ID255743
Gene full namenephronectin
Other gene symbolsEGFL6L POEM
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001657Ureteric bud developmentISSbiological_process
GO:0001658Branching involved in ureteric bud morphogenesisIEA ISSbiological_process
GO:0005178Integrin bindingIEA ISS NASmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005576Extracellular regionISScellular_component
GO:0005578Proteinaceous extracellular matrixISScellular_component
GO:0005604Basement membraneIEAcellular_component
GO:0007160Cell-matrix adhesionIEA ISSbiological_process
GO:0010694Positive regulation of alkaline phosphatase activityIEAbiological_process
GO:0010811Positive regulation of cell-substrate adhesionIEA ISSbiological_process
GO:0016020MembraneIEAcellular_component
GO:0030198Extracellular matrix organizationIEA ISSbiological_process
GO:0030485Smooth muscle contractile fiberIEAcellular_component
GO:0030511Positive regulation of transforming growth factor beta receptor signaling pathwayIEAbiological_process
GO:0033631Cell-cell adhesion mediated by integrinIEA ISSbiological_process
GO:0034678Alpha8-beta1 integrin complexIEAcellular_component
GO:0045184Establishment of protein localizationIEAbiological_process
GO:0045669Positive regulation of osteoblast differentiationIEA ISSbiological_process
GO:0045987Positive regulation of smooth muscle contractionIEAbiological_process
GO:0070374Positive regulation of ERK1 and ERK2 cascadeIEA ISSbiological_process
GO:0071356Cellular response to tumor necrosis factorIEA ISSbiological_process
GO:0097195Pilomotor reflexIEAbiological_process
GO:2000721Positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.26945113790.94969757610.96637462871.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0010850182
GSE13712_SHEARUp0.1328237509
GSE13712_STATICDown-0.1044535155
GSE19018Up0.2067111276
GSE19899_A1Down-0.0335530784
GSE19899_A2Up0.1372893624
PubMed_21979375_A1Up0.1758474796
PubMed_21979375_A2Up0.1014984671
GSE35957Up0.0595586329
GSE36640Up0.0609191718
GSE54402Up0.0888957101
GSE9593Up0.1787669682
GSE43922Up0.0151382106
GSE24585Up0.3648390501
GSE37065Down-0.0256225975
GSE28863_A1Down-0.1419125248
GSE28863_A2Up0.9356202228
GSE28863_A3Up0.0869174425
GSE28863_A4Up0.0552560880
GSE48662Down-0.1461964377

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-378a-3pMIMAT0000732MIRT005422GFP reporter assay//Luciferase reporter assay//Western blotFunctional MTI19844573
hsa-miR-192-5pMIMAT0000222MIRT026404MicroarrayFunctional MTI (Weak)19074876
hsa-miR-425-5pMIMAT0003393MIRT039335CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.