HCSGD entry for RALGAPA1
1. General information
| Official gene symbol | RALGAPA1 |
|---|---|
| Entrez ID | 253959 |
| Gene full name | Ral GTPase activating protein, alpha subunit 1 (catalytic) |
| Other gene symbols | GARNL1 GRIPE TULIP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005096 | GTPase activator activity | IBA IEA | molecular_function |
| GO:0005634 | Nucleus | IBA IEA ISS | cellular_component |
| GO:0005737 | Cytoplasm | IDA ISS | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005829 | Cytosol | IBA | cellular_component |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0017123 | Ral GTPase activator activity | ISS | molecular_function |
| GO:0032859 | Activation of Ral GTPase activity | ISS | biological_process |
| GO:0043547 | Positive regulation of GTPase activity | IBA | biological_process |
| GO:0046982 | Protein heterodimerization activity | IPI | molecular_function |
| GO:0051056 | Regulation of small GTPase mediated signal transduction | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3584730177 | 0.8439341628 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0111212542 |
| GSE13712_SHEAR | Down | -0.0170503113 |
| GSE13712_STATIC | Up | 0.1659446608 |
| GSE19018 | Up | 0.0767844114 |
| GSE19899_A1 | Up | 0.1222767535 |
| GSE19899_A2 | Down | -0.1953903099 |
| PubMed_21979375_A1 | Down | -0.1645668890 |
| PubMed_21979375_A2 | Up | 0.1773593675 |
| GSE35957 | Up | 0.0465187465 |
| GSE36640 | Down | -0.0290492606 |
| GSE54402 | Down | -0.1905615826 |
| GSE9593 | Down | -0.2399589234 |
| GSE43922 | Up | 0.2856431069 |
| GSE24585 | Up | 0.2334142440 |
| GSE37065 | Up | 0.3213483558 |
| GSE28863_A1 | Up | 0.1195249982 |
| GSE28863_A2 | Up | 0.0726171317 |
| GSE28863_A3 | Down | -0.1829960775 |
| GSE28863_A4 | Up | 0.1706963852 |
| GSE48662 | Down | -0.0177273117 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-17-5p | MIMAT0000070 | MIRT051044 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
