HCSGD entry for NEIL2
1. General information
| Official gene symbol | NEIL2 |
|---|---|
| Entrez ID | 252969 |
| Gene full name | nei endonuclease VIII-like 2 (E. coli) |
| Other gene symbols | NEH2 NEI2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003684 | Damaged DNA binding | IEA | molecular_function |
| GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005876 | Spindle microtubule | IEA | cellular_component |
| GO:0006284 | Base-excision repair | IEA | biological_process |
| GO:0006289 | Nucleotide-excision repair | IEA | biological_process |
| GO:0008017 | Microtubule binding | IEA | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016799 | Hydrolase activity, hydrolyzing N-glycosyl compounds | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0664232894 | 0.8665835303 | 0.5552008257 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3950556284 |
| GSE13712_SHEAR | Down | -0.1388135755 |
| GSE13712_STATIC | Up | 0.1833742657 |
| GSE19018 | Down | -0.1297218844 |
| GSE19899_A1 | Up | 0.0762760145 |
| GSE19899_A2 | Up | 1.0205482138 |
| PubMed_21979375_A1 | Up | 0.5801412619 |
| PubMed_21979375_A2 | Up | 1.2837917719 |
| GSE35957 | Down | -0.2330115396 |
| GSE36640 | Up | 0.4947253255 |
| GSE54402 | Up | 0.5313012827 |
| GSE9593 | Up | 0.0092300769 |
| GSE43922 | Up | 0.2213320225 |
| GSE24585 | Down | -0.3105188884 |
| GSE37065 | Down | -0.1628685533 |
| GSE28863_A1 | Down | -0.0016917905 |
| GSE28863_A2 | Up | 0.1849258248 |
| GSE28863_A3 | Down | -0.0859885317 |
| GSE28863_A4 | Down | -0.0381928781 |
| GSE48662 | Down | -0.1865183134 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041564 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
