HCSGD entry for FUCA1
1. General information
Official gene symbol | FUCA1 |
---|---|
Entrez ID | 2517 |
Gene full name | fucosidase, alpha-L- 1, tissue |
Other gene symbols | FUCA |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network

This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0004560 | Alpha-L-fucosidase activity | TAS | molecular_function |
GO:0005737 | Cytoplasm | IC | cellular_component |
GO:0005764 | Lysosome | IBA | cellular_component |
GO:0006004 | Fucose metabolic process | IEA | biological_process |
GO:0006027 | Glycosaminoglycan catabolic process | NAS | biological_process |
GO:0042806 | Fucose binding | IBA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.0691642301 | 0.0513732115 | 0.5628659870 | 0.4262345936 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | Up | 0.5919020024 |
GSE13712_SHEAR | Down | -0.4080219142 |
GSE13712_STATIC | Up | 0.0060948276 |
GSE19018 | Up | 0.3462455677 |
GSE19899_A1 | Down | -0.1101721802 |
GSE19899_A2 | Up | 0.4235421110 |
PubMed_21979375_A1 | Down | -0.9613340120 |
PubMed_21979375_A2 | Up | 0.3480250513 |
GSE35957 | Down | -0.1027493238 |
GSE36640 | Up | 0.9306621176 |
GSE54402 | Down | -0.8839835148 |
GSE9593 | Up | 0.5378848491 |
GSE43922 | Down | -0.1826978168 |
GSE24585 | Up | 0.6082690333 |
GSE37065 | Up | 0.3416337403 |
GSE28863_A1 | Down | -0.8898935716 |
GSE28863_A2 | Up | 1.0402607475 |
GSE28863_A3 | Down | -0.7184733076 |
GSE28863_A4 | Down | -0.4059843926 |
GSE48662 | Down | -0.1453919681 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 3 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
---|---|
23759573 | Senescence-associated lysosomal alpha-L-fucosidase (SA-alpha-Fuc): a sensitive and more robust biomarker for cellular senescence beyond SA-beta-Gal |
23673343 | Here, we identified alpha-L-fucosidase (alpha-Fuc) as a novel sensitive biomarker for cellular senescence |
522513 | On the other hand, no change occurred in alpha-L-fucosidase, alpha-D-mannosidase, alpha-D-galactosidase and alpha-D-glucosidase activities |
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